Leukopenia can involve one or more types of white blood cells and may include neutropenia, monocytopenia,. AML is characterised by an overproduction of immature white blood cells, called myeloblasts or leukaemic blasts. Instead, they are related to thrombocytopenia. Acute leukemia is the most common cancer in children. Symptoms may affect your face, trunk (torso), and extremities and include: papules (small raised bumps on skin) and nodules (lumps under the skin) that typically feel firm or rubbery. Acute lymphocytic leukemia (ALL), on the other hand, does not usually form tumors. Inflammatory leukogram, including a table on how we use terminology to describe changes in mature (segmented) and immature (bands, metamyelocytes etc) neutrophils. Myelodysplastic syndromes (MDSs) Myeloproliferative neoplasms (MPNs) Leukemia is a cancer that starts in the stem cells of the blood. But to make sure this research leads to safe and innovative. What is Luke short for? Nothing, Luke was the name he was given at birth. Leukaemia is a cancer of cells in the bone marrow (the cells which develop into white blood cells). If the IgA blood test results are high, but other immunoglobulin testing results are normal, then this can be an indication that multiple myeloma, leukemia, or lymphoma has developed. Changes in total and differential leukocyte count are usually grouped into patterns, which facilitate interpretation. • Symptoms include fever, chills, fatigue, weakness, weight loss, bone and joint pain, anemia. Generally, leukemia refers to. "to be") – am, is. There are several types of leukemia, which are divided based mainly on whether the leukemia is acute (fast growing) or chronic (slower growing), and whether it starts in myeloid. Your symptoms can be caused by your low monocyte count or by other blood cell abnormalities, such as leukopenia (low white blood cells) or anemia. • Process takes two to four hours and is similar to a regular blood donation. signs of bleeding due to low platelet levels. Prevention. 1b. 1510 /eimí ("is, am") – in the present tense, indicative mood – can be time-inclusive ("omnitemporal," like the Hebrew imperfect tense). Those white blood cells crowd out the red blood cells and platelets. Leukemia is a cancer of the early blood-forming cells. e. Sometimes a health care provider finds it by accident during a blood test for another condition. Risk Factors for Leukemia. leukemia. Dream Meanings Covered in Ants. These abnormal white blood cells are not able to fight infection and impair the ability of the bone marrow to produce red blood cells and platelets. It is more common in children than in adults. Apheresis. Also referred to as hematology/oncology, or heme/onc, this field is focused on diagnosing, treating, and preventing blood, bone marrow, and lymphatic system cancers. Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. AML staging. : leukemia in which the circulating white blood cells are normal or decreased in number. Blood samples for ALL tests are generally taken from a vein in the arm. Exposure to radiation and chemicals such as benzene (found in unleaded gasoline) and other hydrocarbons. These leukemias start in early forms of white blood cells called lymphocytes. leucaemia. ALL is the most common type of cancer and leukemia in children in the United States. [9] These blood cells are not fully developed and are called blasts or leukemia cells. ALL (acute lymphocytic leukemia) is the most common leukemia in children. 2) called the Philadelphia chromosome. Soft tissue sarcomas can develop in soft tissues like fat. : leukemia resulting from changes in the tissues forming white blood cells and characterized by a normal or decreased number of white blood cells in the circulating blood. They build up in the bone marrow and crowd out normal cells. Emergency Management of Blast Crisis. AML affects myeloid cells, which are precursor cells that form into specific blood cells. If acute myeloid leukemia (AML) continues to grow or returns after one type of treatment, other types of treatment might still be helpful. In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis. called also aleukemic myelosis. When someone has this disease, the cells normally. Formerly also leucemia. Researchers have further identified which may cause different types of leukemia. Leukemia is a type of cancer that affects the blood cells, which begins in your bone marrow or other blood-forming tissue. Easy bruising. leukemia definition: 1. loss of appetite. swollen, tender gums. Chronic myelogenous leukemia is a disease in which the bone marrow makes too many white blood cells. 6 x 10 3. 5 – 1. Leukemia is a blood cancer that affects the bone marrow and blood cells. See examples of LEUKEMIA used in a sentence. 14 ), in the bone marrow. Each type of cell has a different job: When you have leukemia, your bone marrow makes large numbers of abnormal cells. Night sweats. 1510 (eimí), and its counterparts, (properly) convey "straight-forward" being (existence, i. A fast or unusual heartbeat. When the word sarcoma is part of the name of a disease, it means the tumor is malignant (cancer). Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). High neutrophils and low lymphocytes together represent an elevated NLR ratio. 9. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. Acute promyelocytic leukemia (APL) is an aggressive type of acute myeloid leukemia (AML). Acute myeloid leukemia (AML): This type of leukemia, also called acute myelogenous leukemia, acute myelocytic leukemia, or acute non. feel dizzy or lightheaded. Fever, chills, night sweats and weight loss, which are collectively known as constitutional or “B” symptoms, are also common in APL. 5 % of red blood cells (up to 2. Benzene has been shown to cause chromosome changes in bone marrow cells in the lab. For women, it is a reading of between 4,500 and 11,000 per μl, and for children between 5,000 and 10,000. A low number of red blood cells is called anaemia. Red blood cells carry oxygen through your body. In general, treatment falls into two phases: Remission induction therapy. 0. 15 U. Blame. Lack of appetite, stomachache, and weight loss. Bone marrow exam Enlarge image. Enlarge. The main treatment for most types of AML is chemotherapy, sometimes along with a targeted therapy drug. Precursor B-cell lymphoblastic leukemia is a form of lymphoid leukemia in which too many B-cell lymphoblasts (immature white blood cells) are found in the blood and bone marrow. It happens when there are too many of the blood-forming cells called promyelocytes in the blood and bone marrow. -emia: or -hemia also -aemia or -haemia suff. • A type of cancer that starts in the bone marrow, where blood is produced. • Involves laboratory medicine, clinical hematology laboratory. Pain in bones/joints. Chronic myelomonocytic leukemia (CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. If ALL spreads to the central nervous system,. leukemia meaning: 1. Acute lymphocytic leukemia (ALL) is a malignancy of B or T lymphoblasts characterized by uncontrolled proliferation of abnormal, immature lymphocytes and their progenitors, which ultimately leads to the replacement of bone marrow elements and other lymphoid organs resulting in a typical disease pattern characteristic of acute. Treatment. Night sweats. Night sweats. Leukemia symptoms vary, depending on the type of leukemia. a serious disease in which the body produces too many white blood cells 2. The spleen also stores white blood cells and platelets. These ranges can vary. Acute myeloid leukemia (AML) is a type of blood cancer. Acute lymphoblastic leukemia (ALL) Acute lymphoblastic leukemia (ALL) is a fast-growing cancer of a type of white blood cells called lymphocytes. leukaemia. [ loo-ke´me-ah] a progressive, malignant neoplasm of the blood-forming organs, marked by diffuse replacement of the bone marrow development of leukocytes and their. Night sweats. As CML progresses, granulocytes take over your bone marrow and blood so that there’s no room for red blood cells, platelets, or healthy white blood cells. Gender: Luke is traditionally the masculine form of the name. Capsule. By contrast, ALL increases the production of lymphocytes. The main types of acute leukemia are: Acute lymphocytic (lymphoblastic) leukemia (ALL): About 3 out of 4 childhood leukemias are ALL. This leads to low numbers of one or more types of blood cells. It starts in places other than the lymph nodes (extranodal). Hematology concerns blood, blood disorders, and bone marrow disease, while oncology is the study of cancer. Leukemia is a type of cancer that affects the blood cells and bone marrow, a soft spongy tissue inside the bones where blood cells are made. Hematologists and oncologists are specialists who treat people who have CML or other types of blood cancer. Posted: January 27, 2023. It's not always. • Treatments include chemotherapy, radiation, stem cell transplant, surgery, immunotherapy. Leukemia cells ultimately occupy the bone marrow, replacing or suppressing the function of cells that develop into normal blood cells. These items can't be displayed right now. They can be classified as acute or chronic based on the rapidity of proliferation and myeloid or lymphoid based on the cell of origin. Read on to learn about the four most common types of leukemia. According to the Natural Resources Defense Council, because of the toxic air pollution resulting. Chronic leukemia develops slowly and may need management over many years. Male sex. It was first studied in 1977. Some of the initial symptoms include. Second, an organization’s form of incorporation and tax-exempt. A headache. • A technology that separates donated blood components to treat certain illnesses. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Ani is short for Anakin and Chewie is short for Chewbacca. The elevation can be caused by many different conditions and may be an indicator of a severe infection, an inflammatory disorder, or cancer. Enlarge. Over time, the abnormal cells overtake the normal cells. [2] [8] Early on, there are typically no symptoms. Leukemia is a malignant condition involving the excess production of immature or abnormal leukocytes, which eventually. 0 to 0. Wang says. Bone marrow biopsy. It has spread to a set of nearby lymph nodes (such as the axillary lymph nodes in breast cancer). Acute myelogenous leukemia (AML) is a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. Leukaemia is a cancer that. Neutrophils are a type of white blood cell that help the body fight infections and heal injuries. When it causes symptoms, hairy cell leukemia might cause: A feeling of fullness in your belly that may make it uncomfortable to eat more than a little at a time. B-cell acute lymphoblastic leukemia is a type of acute lymphoblastic leukemia (ALL). Signs and symptoms of chronic myelogenous leukemia include weight loss and tiredness. Blood Cancers. sore, swollen joints, particularly in the ankles and knees. By contrast, ALL increases the production of lymphocytes. Summary. These stem cells are located in the bone marrow (the spongy. It’s the most common form of leukemia in adults. As CML progresses, granulocytes take over your bone marrow and blood so that there’s no room for red blood cells, platelets, or healthy white blood cells. Leukemia, a cancer of the blood-forming tissues characterized by a large increase in the numbers of white blood cells in the circulation or bone marrow. IG (immature granulocytes) above 1% may indicate infections or chronic inflammation. ”. When we see it, we immediately think “breast cancer awareness. It can sometimes spread to other parts of the body including the lymph nodes, liver, spleen, central nervous system (brain and spinal cord), and testicles. AML causes the body to produce too many myeloblasts, platelets, and red blood cells. CLL typically affects people aged 65 and. Acute lymphocytic leukemia (ALL), also called acute lymphoblastic leukemia, is a cancer that starts from white blood cells called lymphocytes in the bone marrow. C. Symptoms occur as the normal cells fail to perform their tasks, leading to infections and pain. A type of cancer that starts in the bone marrow, moves into the blood cells, and often metastasizes to other parts of the body including the liver, spleen, skin, brain, and spinal cord. Leukemia is a heterogeneous group of hematologic malignancies that arise from the dysfunctional proliferation of developing leukocytes. This causes the number of white blood cells in your body to increase. Smoldering myeloma is a rare, pre-cancerous condition involving abnormal proteins and increased plasma cells in the bone marrow. Acute leukaemia is classified according to the type of white blood cells affected. Learn more. e. Three rarer leukemia types—prolymphocytic leukemia (PLL), large granular lymphocyte leukemia (LGL) and hairy cell leukemia (HCL)—share some of the same characteristics as lymphocytic leukemias and are sometimes considered subtypes of chronic or acute lymphocytic leukemia (CLL and ALL). A buildup of promyelocytes leads to a shortage of other kinds of blood cells, including red cells, white cells, and platelets. Stages I and II are intermediate risk. Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells. Headache and other neurological symptoms. KC presenting to the emergency room unconscious. Myeloproliferative Neoplasms. The field of hematology/oncology can involve many. But it also can affect other lymphoid tissue organs important to the immune system, including: Tonsils. A complete blood count (CBC) is a common medical test that your doctor may recommend to monitor your health. The Janus kinase 2 (JAK2) gene directs cells to make the JAK2 protein, which stimulates cell growth and division. 9. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). Doctors use blood cancer tests to diagnose the leukemia type and plan the best treatment for you. An increase in the TLC count is known as leukocytosis, and it is a condition in which the body produces more WBCs. Both low and high granulocytes can be caused by many different underlying health issues. noun. CML causes an increased number of white blood cells in the blood. Fever. Loss of appetite. leukaemia definition: a serious disease in which the body produces too many white blood cells. A high platelet count is not always a serious concern. The values are higher in infants, ranging from 2 – 6%. Hairy cell leukemia might not cause symptoms. Acute myeloid leukaemia (also called AML or AML leukemia) is a cancer of the blood cells. There are gastric and non-gastric MALT lymphomas. 1 million. 90% to 95% of patients with CML have a shortened chromosome 22 because of a reciprocal translocation t(9;22) (q34;q11. Acute Lymphocytic Leukemia (ALL) in Adults. 1510 (eimí), and its counterparts, (properly) convey "straight-forward" being (existence, i. Keep reading to learn about the terms we use for each stage of the process. These leukaemia cells behave differently from healthy blood cells. Note. This product is available in the following dosage forms: Tablet. The term "chronic" in chronic myelogenous leukemia means this cancer tends to progress more slowly than. In its early stages, the symptoms of AML may resemble the flu and you may have a fever and fatigue. Cancer is a disease of the cells in the body. Leukemia has several possible causes. These are not just symptoms of AML. This type of cancer usually gets worse quickly if it is not treated. Lumps caused by swollen lymph nodes in and around the neck, armpits, abdomen or groin. What is Luke short for? : r/AntiJokes. High levels of eosinophils can indicate cancer (e. They may happen if the initial treatment doesn’t eliminate all. Your claim status tells you where your claim is in the review process. without explicit limits). It starts in your bone marrow, the soft inner parts of bones. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features NFL Sunday Ticket Press Copyright. It happens when blood cells. AML is rare. This chromosome is. The samples are usually taken from the back of the pelvic (hip) bone, but sometimes other bones are. Putting it together. Therefore AML is not staged like most other cancers. This was shortened to Luke in English. “Therapies that we use for blood cancers are, unfortunately, not 100% specific for the eradication of blood cancer cells and can attack some normal blood cells such as platelets, too," Dr. Leukemia is a cancer of the early blood-forming cells. A decrease in normal blood cells causes the symptoms of leukemia. It happens when healthy white blood cells ( lymphocytes) in your bone marrow mutate, or change, into cancerous cells that multiply and crowd out healthy blood cells and platelets. These leukemias start in early forms of white blood cells called lymphocytes. Bone marrow is the soft tissue in the center of bones that helps form all. There are no symptoms of high monocytes. However, high immature granulocyte levels can also be normal during pregnancy and in newborns. The study followed more than. . In lymphoma, cancerous white blood cells form tumors in. They are measured by the number of white blood cells per cubic millimeter of blood (cells/mm3). Accelerated phase, 10% to 19% of the cells in the. CML staging. When symptoms are present, an enlarged spleen may cause: pain in the upper left side of your abdomen. cancer of the blood. A low platelet count means your blood lacks the small cells it needs to form clots. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood cells called the myeloid. Keeping track of your lab results lets your doctor take action as soon as your blood counts. Nausea, vomiting, diarrhea. The four main types of leukaemia are:Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer; it also strikes adults of all ages. This medicine is available only with your doctor's prescription. Colors: Blue, marigold, and purple. It generally affects all of the bone marrow in the body and, in some cases, has already spread to other organs, such as the liver, spleen, and lymph nodes, by the time it is found. Metaplasia is an abnormal condition in which healthy mature cells are replaced by a different kind of mature cell that should not be in that tissue. Origin: Luke from the Bible, a physician who was a disciple of St. Your bone marrow produces white blood cells, red blood cells, and platelets. a disease in which…. Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) was previously known as natural killer (NK) cell leukemia/lymphoma. People with familial acute myeloid leukemia with mutated CEBPA have a shortage of white blood cells (leukopenia), leading to increased susceptibility to infections. entity, regardless of whether it is a “corporation” within the meaning of Section 4. Bruises are common after an injury, but they may be a sign of. The main types of acute leukemia are: Acute lymphocytic (lymphoblastic) leukemia (ALL): About 3 out of 4 childhood leukemias are ALL. 2. This stem cell goes through stages of development. There is some lab-to-lab variability in ranges due to differences in equipment. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. Certain genetic abnormalities, such as Down syndrome. Men. When you have leukemia, your body makes too many blood cells, which are abnormal. Anemia can be a problem for people living with leukemia, and it can have a significant impact on someone’s quality of life. These symptoms include: fatigue. easy. Luke Emia is a two-time character that appears in "Cody's New Friend!" and "Brooklyn Guy The Liar!". It’s the most common type of cancer in children, but can also affect adults. It’s the most common form of leukemia in adults. 4,500–11,000. Benzene evaporates into the air very quickly. The bone is made up of compact bone, spongy bone, and bone marrow. Great takers. There are different types of leukemia. Chronic lymphocytic leukaemia is a rare type of cancer that affects the blood and bone marrow. A condition known as eosinophilia , high levels are described as mild (500 to 1,500 per microliter, ml, of blood), moderate (1,500 to 5,000 per ml), or severe (5,000 or more per ml). They can be classified as acute or chronic based on the rapidity of proliferation and myeloid or lymphoid based on the cell of origin. 5. Leukemia is a broad term for cancers of the blood cells. Leukemia. This cancer occurs primarily in older individuals, with a median age of diagnosis. Takeaway. Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) is an indolent malignancy characterized by increased production of mature but dysfunctional B lymphocytes. The caviar or fish eggs of sturgeon, cod, salmon, hake or tuna are considered a coveted dish and of the high cooking. 4572 HighlightsJune 4, 2012. It is the most common form of non-Hodgkin lymphoma among adults, with an annual incidence of 7–8 cases per 100,000 people per year in the US and UK. The fusion oncoprotein BCR-ABL1 defines CML. The detection of chromosomal translocations can be important for the diagnosis of certain genetic diseases and disorders. White blood cells (leukocytes) are used by the body to fight infections and other foreign substances. Treatment depends on the type of leukemia but generally involves. [1] Most of the health concerns associated with polycythemia vera are caused by the blood being thicker as a result of the increased red blood cells. Take, for example, breast cancer awareness. 5–15. Most often, leukemia is a cancer of the white blood cells, but some leukemias start in other blood cell types. Abnormally low neutrophil count (neutropenia) as well as a high lymphocyte count (lymphocytosis) can be the result of viral infection or an indication of the adult-onset form of cyclic neutropenia, certain lymphoproliferative disorders like lymphomas and leukemias or certain autoimmune diseases. It is more common in children than in adults. "to be") – am, is. What is Luke short for? : r/AntiJokes. Parts of the respiratory tract. Blood tests are done to help watch your body’s response to treatment. If you have anaemia, you might: look pale. According to the National Cancer Institute, B-cell acute lymphoblastic leukemia is the most common. Early on, there are typically no symptoms. Bone pain. Acute lymphocytic leukemia (ALL) is a cancer of the blood and bone marrow. 10. High levels of neutrophils may indicate a severe infection or stress on the body. Often, it divides to make new cells faster than normal. It affects white blood cells, which your body needs to fight infection. Leukemia starts in blood-forming tissues such as the bone marrow. ThrombocytopeniaLeukemia is a type of blood cancer that affects the blood cells and bone marrow, a tissue inside bones where blood cells and platelets are made. SEER is an authoritative source for cancer statistics in the United States. A high absolute neutrophil count is called neutrophilia . low red blood cell count. Acute lymphocytic (or lymphoblastic) leukemia is sometimes called ALL. Leukemia Definitions and Meaning in English. تشمل العلامات والأعراض المعتادة لابيضاض الدم: الحمى أو القشعريرة. To Lubick, that has meant finding purpose and meaning within a different type of adversity. It is most common in people who are older. tiredness and/or anaemia (pale complexion, weakness and breathlessness) repeated infections (mouth sores, sore throat, fevers, sweats, coughing, frequent passing of urine with irritation, infected cuts and scratches, and boils) increased bruising and bleeding. Getting a diagnosis. Long-term exposure to benzene. Dream Meaning ten pin Bowling. It's a type of cancer that starts in cells that become certain white blood cells (called lymphocytes) in the bone marrow. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of. CLL/SLL is defined as a monoclonal lymphoproliferative disease characterized by the proliferation and accumulation of morphologically mature but. Key takeaways: The FVRCP vaccine protects cats against three highly contagious and dangerous diseases. Only the context indicates. MCL is the rarest form of systemic mastocytosis, making up less than 1 percent of cases. Long-term exposure to benzene. High monocytes can also be a side effect of medication. Most often, leukemia is a cancer of the white blood cells, but some leukemias start in other blood cell types. Symptoms of low red blood cell count (anemia), such as fatigue, pale skin, and shortness of breath. A type of cancer that starts in the bone marrow, moves into the blood cells, and often metastasizes to other parts of the body including the liver, spleen, skin, brain, and spinal cord. 26. Learn more about the types, symptoms, diagnosis, and treatment of leukemia. Pain, including in your. : a disease of cats caused by the feline leukemia virus, characterized by leukemia and lymphoma, and often resulting in death. What is Luke short for? Nothing, Luke was the name he was given at birth. spiritual meaning of leukemia. Contents Overview Symptoms and Causes Diagnosis. A person may notice them before they receive a diagnosis. It is characterized by an extremely elevated blast cell count and symptoms of decreased tissue perfusion. The cancer (leukemia) cells start in the bone marrow but then go into the blood. ( lū-kē'mē-ă ), Progressive proliferation of abnormal leukocytes found in hemopoietic tissues, other organs, and usually in the blood in increased numbers. Pain in bones/joints. In this article, we take a look at how. population. Swollen lymph nodes in your neck, armpits, stomach, or groin; lymph nodes are pea-sized glands in these and other areas of your body. In cancer care, this blood test can be used to help diagnose a cancer or monitor how cancer or its. Low red blood cells lead to anemia: Headaches, lightheadedness, shortness of breath, pallor and fatigue. Your outlook will depend on what type of blood cells the cancer. Eventually, symptoms may include any of the following: Anemia and related symptoms, such as fatigue, pallor, and a general. Different types of leukaemia are named according to: the type of blood cell which is affected. The American Cancer Society offers free information in Hindi about cancer prevention, early detection, treatment, and survivorship. Getting a diagnosis. Other less common symptoms include: bone pain. The blood’s cellular components originate primarily in the marrow of bones such as the sternum, iliac crest, and cranium. On this page. Leukemia has several possible causes. CLL is typically found when you get a blood test for another reason. This is a condition where high levels of lgM interfere with the cells that produce lgG, preventing their growth. g. Pathophysiology. It is modified and given essential meaning by the suffix ~emia, meaning _____ _____. Learn more. Standard treatment usually helps in this phase. MCH stands for Mean Corpuscular Hemoglobin, and is a calculation of the average amount of hemoglobin contained in each of a person’s red blood cells. Leukemia is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. If your spleen is too big you might feel a fullness in your belly. Leukemia cutis characteristically demonstrates the infiltration of the skin by neoplastic leukocytes. These include: recurring infections. Research has also noted several. Many people with chronic lymphocytic leukemia have no symptoms at first. A decrease in the TLC count is referred to as leukopenia, and it will cause a decline in the body’s ability to fight diseases. The blast cells have spread to tissues and organs beyond the bone marrow. Anatomy of the bone. It’s a genetic disease, but most cases aren’t thought to be hereditary. S. Luke Emia is a two-time character that appears in "Cody's New Friend!" and "Brooklyn Guy The Liar!". Leukostasis is a pathologic diagnosis in. Updated October 2022 2 Any of the anxiety states Dysthymic disorder (or depressive neurosis) Organic residuals of frostbite Post-traumatic osteoarthritisChronic lymphocytic leukaemia is a rare type of cancer that affects the blood and bone marrow. frequent nosebleeds. Acute lymphocytic leukemia is a type of acute leukemia. Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) was previously known as natural killer (NK) cell leukemia/lymphoma. A relapse is when cancer comes back after treatment.